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Weight Loss Drug Shows Potential Benefit for Type 2 Diabetes

Researchers at the University of Liverpool have found that the weight loss drug, Tirzepatide is associated with significantly reduced risk of developing type 2 diabetes (T2D).
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Morphable Materials: Researchers Coax Nanoparticles To Reconfigure Themselves

A view into how nanoscale building blocks can rearrange into different organized structures on command is now possible.
Cancer cells.
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New Targeted Therapy Shows Promise in Slowing Endometrial Cancer Growth

Researchers discovered that targeting the ERBB2 gene in mice with PTEN mutations significantly slowed endometrial cancer growth. This finding offers hope for alternative treatments beyond hysterectomy and aggressive therapies.
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Improving AlphaFold2 by Teaching It To Focus on “Energetic Frustration”

By encouraging AlphaFold2 to focus on "energetic frustration", researchers have found a new way to predict how proteins change shape.
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New Technique May Reveal Repurposing Potential for Existing Drugs

A new technique may help reveal unknown benefits of existing drugs, according to a new study. The new approach, called decryptE, could help identify new applications for already approved drugs and take steps toward precision medicine.
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Early Antibiotic Use in Infants Leads to Lifelong Allergies

Researchers found that depleting gut bacteria in newborns through antibiotics leads to lifelong allergies. This discovery opens doors to potential new treatments targeting allergies at their source.
A tube of Naloxone.
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Naloxone Administration in Cardiac Arrest Cases Shows Promising Results

A UC Davis Health study found that naloxone improves outcomes in opioid-associated out-of-hospital cardiac arrests (OHCA), leading to both increased return of spontaneous circulation and survival to hospital discharge.
A freshly-collected batch of venomous cone snails.
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Deadly Snail Venom Could Hold the Key to New Diabetes Treatments

Researchers discovered a hormone-like toxin in cone snail venom that mimics human somatostatin, regulating blood sugar and hormone levels with greater stability and specificity.
A white mouse climbing over test tubes.
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Advancing Non-Animal Testing: New Software Reveals Gaps in Chemical Risk Models

University of Vienna researchers developed MolCompass, a tool that identifies blind spots in machine learning models used for chemical risk assessment. The tool aims to increase transparency and confidence in computational models.
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Study Examines Effect of Alzheimer's Drug on Tissue Samples from People with Down Syndrome

A study found that lecanemab effectively targets amyloid plaques in brain tissue of people with Down syndrome, who are prone to early Alzheimer's. While promising, the drug also binds to brain blood vessels, raising safety concerns.
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