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Latest App Notes & Case Studies

Picus® 2 Sustainability Fact Sheet
App Note / Case Study

Picus® 2 Sustainability Fact Sheet

Sartorius Picus® 2 electronic pipettes are the ideal tools to accompany you in daily, repetitive liquid handling in laboratories, where the accuracy of your results, speed and ergonomics are important.
Purple and blue background with falling transparent particles in the foreground
App Note / Case Study

A Powerful Tool for Bioanalysis in Complex Matrices

This app note highlights a system that can minimize downstream ion path contamination, maintaining the highest levels of sensitivity and stability over an extended period.
Microscopic view of fluorescently labeled cells showing green cell bodies with blue nuclei connected by thin, bridge-like structures
App Note / Case Study

Studying the Link Between Cell Migration and Neurodegenerative Disease With iPSC-derived Microglia

In this application note, researchers from Medicines Discovery Catapult (MDC) evaluated the suitability of iPSC-derived microglia as a model for studying the mechanics of microglia activation, shedding light on their role in neurodegeneration and the potential for therapeutic targets.
A doctor writing on a clipboard next to a brain, examining medical records and analyzing brain functions
App Note / Case Study

Improving Physiological Relevance in Neurological Disease Drug Development

This app note explores the use of human iPSC-derived microglial cells as a more reliable model for neurobiological drug development.
Cancer cells under a microscope, showing abnormal growth and division.
App Note / Case Study

A Rapid and Robust Solution for Cellular Response Characterization

This app note explores the use of an assay to facilitate rapid monitoring of T-cell function and simultaneous assessment of cell phenotype, activation markers, proliferation, viability and cytokine secretion.
Liver Fibrosis
App Note / Case Study

A Novel Approach for Non-Invasive Liver Research

This case study utilizes non-invasive ultrasound imaging to visualize and quantify liver echogenicity and stiffness, providing critical insights into both disease progression and the efficacy of therapeutic interventions in mouse models.
Assessing the Functionality of PBMCs After Cryopreservation
App Note / Case Study

Assessing the Functionality of PBMCs After Cryopreservation

As PBMCs continue to see an increase in use in the testing of new biological therapeutic compounds, ensuring purified cells retain functionality after cryopreservation is critical.
engineered stable mAbs
App Note / Case Study

Biologics Developability: Optimization of Engineered mAbs With Multi-Parameter Stability Characterization

The biologic drug development process is expensive and often leads to time and money lost on candidates that never reach the clinic. Improved developability profiles enable researchers in the early discovery stages to select candidates that have a great chance at clinical success.
Neuro Research
App Note / Case Study

Speeding Up Neuroscience Research

Delve into this case study to explore how a research lab at King’s College London used hiPSC-derived neurons to shed light on synaptic biology and potential treatments for psychiatric conditions.
Neuro Program
App Note / Case Study

Precision Reprogrammed iPSC Models for High-Throughput Drug Discovery

This app note delves into the role of TDP-43 protein aggregates in the disease's progression. Charles River Laboratories and bit.bio present a breakthrough in ALS research with genetically matched ioGlutamatergic Neurons, providing a crucial in vitro model.
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