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A DNA molecule with tweezers editing part of the molecule
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Hundreds of Patients in England To Benefit From the World's First Gene Editing Therapy

Patients in England with severe beta-thalassaemia will be amongst the first in Europe to benefit from one-time gene therapy exagamglogene autotemcel (“exa-cel”, also called Casgevy and made by Vertex).
A needle going into a vaccine vial bottle.
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How the BCG Vaccine Uses Macrophages to Fight Bladder Cancer

This may come as a surprise, but the BCG vaccine against tuberculosis is the oldest immunotherapy against cancer. Now, a team from the Champalimaud Foundation, in Lisbon, has found the first steps of its action to destroy cancer cells.
A woman having an eye test.
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Glaucoma Research Reveals Potential Gene Therapy Target

A new study looks into how deficiency of the enzyme NMNAT2 renders the nerve cells of the eye vulnerable to neurodegeneration and could be a key in the search for a treatment.
A row of vaccines vials.
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Potential Vaccine and Treatment Developed for Flu and Coronaviruses

A team of researchers has discovered two new ways of preventing and treating respiratory viruses. The team reports the development and validation of NanoSTING, a nasal spray, and the development of NanoSTING-SN, a pan-coronavirus nasal vaccine.
A gloved hand holds a syringe of yellow liquid.
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Immune Atlas Reveals Why Vaccines Have Lower Efficacies in Multiple Myeloma Patients

Alterations in the composition of immune cells in multiple myeloma patients can influence the efficacy of vaccines, a new immune atlas reveals.
Treated human stem cells transplanted into a laboratory animal.
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Researchers Develop Cells that Prevent Malignant Growth

Researchers at the University of Helsinki and HUS Helsinki University Hospital succeeded in creating cells whose proliferation can be controlled. The technique enables new and safe cell therapies.
Cell therapy.
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Promising Glioblastoma Therapy Targets Newly Discovered Pathway in Preclinical Models

A team of research groups discovered that a migration path used by cells during brain development can be hijacked for cancer cell invasion, opening up new opportunities for treating aggressive brain cancers like glioblastoma.
A cancer patient in a hospital bed with a drip attached to their arm.
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Novel Solution Devised To Prevent Relapse After CAR T-Cell Therapy

A new technique to help CAR T-cells persist longer in the body and form a memory of the cancer cell could prevent cancer recurrence.
Seaweed surrounding a human brain.
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Seaweed Antioxidant Restores Motor Function in Parkinson’s Model

Ecklonia cava is a seaweed that may hold the key to Parkinson’s disease prevention. In this study, two types of motor function tests were conducted using Parkinson’s disease model mice that were orally fed the antioxidants daily for one week.
A Nubian spitting cobra (Naja nubiae).
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CRISPR Identifies Common Blood Thinner as Snake Venom Antidote

Researchers at the University of Sydney and Liverpool School of Tropical Medicine demonstrated how a commonly used blood thinner could be repurposed as a cost-effective and easy-to-access cobra venom antidote.
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